Cortical Reorganisation (CoRe) Study - sponsored by Cambridge University Hospitals NHS Foundation Trust and The University of Cambridge
Some research studies have previously found subtle changes in the structure and function of the brain in CRPS. Many people with CRPS also have difficulties in accurately perceiving sensations from the body, but it is unknown whether this is related to brain changes. The CoRe study investigated these brain changes, to determine whether there is a link with the inability to perceive body sensations accurately.
The study was a collaboration between the University of Cambridge and the University of Liverpool. People with CRPS who were recruited into the study were asked to complete questionnaires to assess their level of pain, function and mood. They also had clinical tests to measure body perceptions, brain activity (EEG), and brain structure (MRI scan).